The Solid Tissue section provides a diagnostic service mainly for products of conception, stillbirth and IUD.
Samples are analysed initially by QF-PCR and then if appropriate by Microarray.
Prenatal
- Any fetus, stillbirth or neonatal death with congenital abnormality suggestive of a chromosome anomaly or with neural tube defect or with IUGR.
- Abnormal ultrasound scan, including hydatidiform mole and “blighted ovum”
- Known familial chromosome rearrangements
- Previous chromosomally abnormal child
- Miscarriage from IVF pregnancy
- Third or more miscarriage.
Samples must be sent for post mortem examination by the Pathology laboratory, Royal Infirmary, Little France. Biopsies will be taken by the Paediatric Pathologist who will forward to Cytogenetics if appropriate.
Postnatal
- Tissue specific syndromes (please discuss with the laboratory before sending)
Tissue Biopsies for Metabolic Studies
The laboratory no longer accepts samples for culture and dispatch to other laboratories for metabolic studies. Please contact the Dept of Cytogenetics, ,West of Scotland Centre for Genomic Medicine, Laboratory Genetics, Level 2B Laboratory Medicine & FM Building, Queen Elizabeth University Hospital, Glasgow, G51 4TF. Tel 0141 354 9300.
Details of Limitations of Cytogenetics Investigations are available.
