Loading...
Neuroprogressive and Dementia Network NHS Lothian | Our Services

Current Studies: Dementia Studies

We are currently running a range of dementia research studies across Edinburgh and the Lothians. Some of our studies are also taking place in other parts of Scotland.

If you are interested in participating in research, you can register online or email us: loth.sdcrn@nhs.scot

By taking part, you can help advance understanding, improve treatments, and shape the future of dementia care.

Open to Recruitment

Icon for the COBALT trial

COBALT: COmBining memantine And cholinesterase inhibitors in Lewy body dementia treatment Trial

A clinical trial to see if the medicines memantine and cholinesterase inhibitors can help improve symptoms for people with Parkinson’s disease dementia or Dementia with Lewy Bodies.

Icon for Dementia Plaform UK

FAST: Feasibility and Acceptability of Scalable Tests

A research study trying to better understand a person’s risk for developing Alzheimer’s Disease, using digital cognitive assessments and blood tests.

Upcoming Studies

Icon for Bristol Myers Squibb

MINDSET 2: A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer’s Disease 

A clinical trial to see if the medicines KarXT and KarX-EC can help improve memory and thinking for people with Alzheimer’s disease.

FIESTA

FIESTA: Focused Investigation of the Efficacy and Safety of Tadalafil in Alzheimer’s Disease

A clinical trial to see if the medication tadalafil can help with memory and thinking in the early stages of Alzheimer’s Disease dementia OR with Mild Cognitive Impairment.

Prima Mente

SANDBOX: Scalable Assessment of Neurodegenerative Diagnosis via Biomarkers and Online Examination

This research study is trying to better understand how to improve the diagnostic processes in the NHS for Alzheimer’s Disease dementia by introducing blood-based biomarker tests and digital memory and thinking tasks

Other Ongoing Studies

Closed to recruitment

DPUK

DFP: Combinatorial Biomarkers for Dementia Experimental Medicine

A research study trying to better understand a person’s risk for developing Alzheimer’s Disease, using digital cognitive assessments and blood tests.

EVOKE

EVOKE/ EVOKE+: Investigating Semaglutide in People with Early Alzheimer’s Disease ​

A clinical trial to see if the medicine Semaglutide can help slow down memory and thinking problems for people with Alzheimer’s disease.

CONTACT INFORMATION

Neuroprogressive & Dementia Research Network Office


Old Pharmacy Building
Western General Hospital
Edinburgh
EH4 2XU

Email: loth.sdcrn@nhs.scot

Telephone: 0131 537 3804

ABOUT US

The NRS Neuroprogressive Disease and Dementia Network team in NHS Lothian conduct commercial and investigator led studies for: Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Motor Neurone Disease, dementia with Lewy bodies, Progressive Supranuclear Palsy and Multiple System Atrophy.

© NHS LOTHIAN | YOUR SERVICE.

Carer Positive Icon
Awards Aware Icon
We are a Living wage Employer Icon
Duke of Edinburgh's Award Logo
Young Person's Guaranteed Employer Logo
Scottish Top Employers Logo
Disability Confident Employer Logo

 
NHS Lothian Charity Logo
Tel: +44 (0)131 465 5850
Email: loth.charity@nhs.scot

Scottish Registered Charity No: SC007342
The official charity of NHS Lothian.
From the everyday to the transformational, we support NHS Lothian to excel for all the communities it serves: patients, families, carers and staff.
Making healthcare better, together.