We are currently running a range of dementia research studies across Edinburgh and the Lothians. Some of our studies are also taking place in other parts of Scotland.
If you are interested in participating in research, you can register online or email us: loth.sdcrn@nhs.scot
By taking part, you can help advance understanding, improve treatments, and shape the future of dementia care.
Open to Recruitment

COBALT: COmBining memantine And cholinesterase inhibitors in Lewy body dementia treatment Trial
A clinical trial to see if the medicines memantine and cholinesterase inhibitors can help improve symptoms for people with Parkinson’s disease dementia or Dementia with Lewy Bodies.

FAST: Feasibility and Acceptability of Scalable Tests
A research study trying to better understand a person’s risk for developing Alzheimer’s Disease, using digital cognitive assessments and blood tests.
Upcoming Studies

A clinical trial to see if the medicines KarXT and KarX-EC can help improve memory and thinking for people with Alzheimer’s disease.

FIESTA: Focused Investigation of the Efficacy and Safety of Tadalafil in Alzheimer’s Disease
A clinical trial to see if the medication tadalafil can help with memory and thinking in the early stages of Alzheimer’s Disease dementia OR with Mild Cognitive Impairment.

SANDBOX: Scalable Assessment of Neurodegenerative Diagnosis via Biomarkers and Online Examination
This research study is trying to better understand how to improve the diagnostic processes in the NHS for Alzheimer’s Disease dementia by introducing blood-based biomarker tests and digital memory and thinking tasks
Other Ongoing Studies
Closed to recruitment

DFP: Combinatorial Biomarkers for Dementia Experimental Medicine
A research study trying to better understand a person’s risk for developing Alzheimer’s Disease, using digital cognitive assessments and blood tests.

EVOKE/ EVOKE+: Investigating Semaglutide in People with Early Alzheimer’s Disease
A clinical trial to see if the medicine Semaglutide can help slow down memory and thinking problems for people with Alzheimer’s disease.












