MINDSET 2

MINDSET 2

This clinical trial looks to see if the medications KarXT + KarX-EC improve memory and thinking problems in people with Alzheimer’s Disease.

What Happens In This Study?

You will either be given medicines called KarXT + KarX-EC or two placebos (dummy pills that looks like the medicine but have no active ingredients). Neither you, nor the research team, will know which group you are in.

Can I Join This Study?

To take part in this medical trial, you must meet these 8 requirements:

1. Your Diagnosis: A doctor must have confirmed that you have Alzheimer’s disease.
2. Your Symptoms: Your Alzheimer’s symptoms should be mild or moderate. A doctor will be able to assess your symptom severity.
3. Your Age: You are between 60 and 85 years old.
4. Your Study Partner: You must have a reliable friend of family member who knows you well and you see regularly, who can also take part to provide us with information on how you are doing.
5. Your Current Medicine: If you are taking Alzheimer’s disease medication, you must have been taking this for at least 3 months, without making any big changes to it.
6. Your Permission: You must be able to understand what happens in the study and sign a form (called informed consent) to say you agree to join.
7. Your Time: You must do your best to attend all your study visits, and follow the rules of the study until it ends.
8. Taking the Medicine: You must be willing and able to swallow the trial medication.

Study Length: 24 weeks (with an optional additional 24 weeks where you are guaranteed to be on the medication)

Number of appointments: 12 visits (with an optional additional 7 visits)

More information on the trial can be found on the BMS website.