This clinical trial looks to see if the medication ambroxol can slow or halt the progression of Parkinson’s disease.

What Happens In This Study?

You will either be given a medicine called ambroxol or a placebo (a dummy pill that looks like the medicine but has no active ingredients). Neither you, nor the research team, will know which group you are in.

Can I Join This Study?

To take part in this medical trial, you must meet these 8 requirements:

1. Your Diagnosis: A doctor must have confirmed that you have Parkinson’s disease. This needs to have happened within the last 7 years.
2. Your Age: You are between 35 and 75 years old.
3. Your Symptoms: Your Parkinson’s symptoms should be mild or moderate. A doctor will be able to assess your symptom severity.
4. Your Genes: You must know your GBA1 gene status. Your doctor will be able to tell you if this information is available.
5. Your Current Medicine: You must have been taking the same Parkinson’s medication for at least the last 3 months without making any big changes to it.
6. Your Permission: You must be able to understand what happens in the study and sign a form (called informed consent) to say you agree to join.
7. Your Time: You must do your best to attend all your study visits, and follow the rules of the study until it ends.
8. Taking the Medicine: You must be willing and able to swallow the trial medication.

Study Length: 90 weeks (1 year and 10 months)

Number of appointments: 7 visits, plus check in phone calls

More information on the trial can be found on the Aspro-PD website.