Scroll down to find out more about our current clinical research studies
If you are interested in participating in research, you can register through Permission to Contact or email us on loth.sdcrn@nhs.scot
Open to Recruitment
Dementia Studies
COBALT: COmBining memantine And cholinesterase inhibitors in Lewy body dementia treatment Trial
Trialing memantine and cholinesterase inhibitors for Parkinson’s disease dementia or Dementia with Lewy Bodies
Huntington’s Studies
ENROLL-HD: A Prospective Registry Study in a Global Huntington’s Disease Cohort
The largest observational study globally for Huntington’s disease
iMark HD: Investigating biomarkers for disease and symptom progression in Huntington’s disease
Using Magnetic Resonance Imaging scans and Positron Emission Tomography scans to search for biomarkers to highlight early disease processes, and disease progression in Huntington’s disease
Parkinson’s Studies
COBALT: COmBining memantine And cholinesterase inhibitors in Lewy body dementia treatment Trial
Trialing memantine and cholinesterase inhibitors for Parkinson’s disease dementia or Dementia with Lewy Bodies
PD Frontline: genetic testing provision to facilitate clinical trial referral for people with Parkinson’s
Offering online genetic testing for individuals with Parkinson’s disease to ascertain eligibility for other Parkinson’s disease trials
TOP HAT: Trial of Ondansetron as a Parkinson’s Hallucinations Treatment
Trialing ondansetron as a treatment for Parkinson’s hallucinations
Upcoming Studies
Dementia Studies
MINDSET 2: A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer’s Disease
To determine whether KarXT + KarX-EC can improve memory and thinking in Alzheimer’s Disease.
FAST: Feasibility and Acceptability of Scalable Tests
To explore Alzheimer’s Disease risk using digital cognitive assessments and blood tests.
Parkinson’s Studies
ASPRO PD: Ambroxol for Flowing the Progression of Parkinson’s Disease
To determine whether ambroxol can slow or halt Parkinson’s disease progression .
Other Ongoing Studies
Dementia Studies
DFP: Deep and Frequent Phenotyping; Combinatorial Biomarkers for Dementia Experimental Medicine
Tracking biological and cognitive markers of Alzheimer’s disease to detect disease change
EVOKE/ EVOKE+: Investigating Semaglutide in People with Early Alzheimer’s Disease
A randomized, double-blind, placebo-controlled study to investigate potential benefits for reducing cognitive decline in Alzheimer’s disease.
Huntington’s Studies
HealthE-RND: Advancing E-Health for Huntington’s Disease and Beyond
Improving access to multidisciplinary care for people affected by Huntington’s disease
Parkinson’s Studies
CAN-PDP: CANnabidiol for Parkinson’s Disease Psychosis
A clinical trial investigating cannabidiol as a safe treatment for reducing hallucinations and delusions in Parkinson’s.
Probiotic: Investigating the effects of B. Subtilis Bacteria on the microbiome in Parkinson’s Disease
To determine whether B. Subtilis PXN21 has any beneficial effects on gut microbiome composition and Parkinson’s Disease symptoms.
