{"id":2118,"date":"2026-03-09T12:34:00","date_gmt":"2026-03-09T12:34:00","guid":{"rendered":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/?page_id=2118"},"modified":"2026-03-09T16:49:15","modified_gmt":"2026-03-09T16:49:15","slug":"current-studies-dementia-studies","status":"publish","type":"page","link":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/current-studies-dementia-studies\/","title":{"rendered":"Current Studies: Dementia Studies"},"content":{"rendered":"\n<p>We are currently running a range of dementia research studies across Edinburgh and the Lothians.  Some of our studies are also taking place in other parts of Scotland.<\/p>\n\n\n\n<div class=\"wp-block-group has-light-accent-grey-background-color has-background\" style=\"border-top-left-radius:50px;border-top-right-radius:50px;border-bottom-left-radius:50px;border-bottom-right-radius:50px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h4 class=\"wp-block-heading has-text-align-center\">If you are interested in participating in research, you can&nbsp;<a href=\"https:\/\/www.nhsresearchscotland.org.uk\/research-areas\/dementia-and-neurodegenerative-disease\/patient-signup-form\" target=\"_blank\" rel=\"noopener\">register online<\/a>&nbsp;or email us: <a href=\"mailto:loth.sdcrn@nhs.scot\">loth.sdcrn@nhs.scot<\/a><\/h4>\n\n\n\n<p class=\"has-text-align-center\">By taking part, you can help advance understanding, improve treatments, and shape the future of dementia care.<\/p>\n\n\n\n<div class=\"wp-block-group has-standard-white-background-color has-background\" style=\"border-top-left-radius:50px;border-top-right-radius:50px;border-bottom-left-radius:50px;border-bottom-right-radius:50px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">Open to Recruitment<\/h2>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:35% auto\"><figure class=\"wp-block-media-text__media\"><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/cobalt\/\"><img loading=\"lazy\" decoding=\"async\" width=\"917\" height=\"592\" src=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/COBALT-2.png\" alt=\"Icon for the COBALT trial\" class=\"wp-image-2128 size-full\" srcset=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/COBALT-2.png 917w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/COBALT-2-300x194.png 300w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/COBALT-2-768x496.png 768w\" sizes=\"auto, (max-width: 917px) 100vw, 917px\" \/><\/a><\/figure><div class=\"wp-block-media-text__content\">\n<p><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/cobalt\/\">COBALT: <strong>COmBining memantine And cholinesterase inhibitors in Lewy body dementia treatment Trial<\/strong><\/a><\/p>\n\n\n\n<p>A clinical trial to see if the medicines memantine and cholinesterase inhibitors can help improve symptoms for people with <strong>Parkinson\u2019s disease dementia<\/strong> or <strong>Dementia with Lewy Bodies<\/strong>.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:35% auto\"><figure class=\"wp-block-media-text__media\"><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/fast-study\/\"><img loading=\"lazy\" decoding=\"async\" width=\"916\" height=\"592\" src=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/DPUK-1.png\" alt=\"Icon for Dementia Plaform UK\" class=\"wp-image-2130 size-full\" srcset=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/DPUK-1.png 916w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/DPUK-1-300x194.png 300w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/DPUK-1-768x496.png 768w\" sizes=\"auto, (max-width: 916px) 100vw, 916px\" \/><\/a><\/figure><div class=\"wp-block-media-text__content\">\n<p><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/fast-study\/\">FAST<strong>: Feasibility and Acceptability of Scalable Tests<\/strong><\/a><\/p>\n\n\n\n<p>A research study trying to better understand a person&#8217;s risk for developing <strong>Alzheimer&#8217;s Disease<\/strong>, using digital cognitive assessments and blood tests.<\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group has-standard-white-background-color has-background\" style=\"border-top-left-radius:50px;border-top-right-radius:50px;border-bottom-left-radius:50px;border-bottom-right-radius:50px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">Upcoming Studies<\/h2>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:35% auto\"><figure class=\"wp-block-media-text__media\"><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/mindset-2\/\"><img loading=\"lazy\" decoding=\"async\" width=\"916\" height=\"592\" src=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/BMS-2.png\" alt=\"Icon for Bristol Myers Squibb\" class=\"wp-image-2129 size-full\" srcset=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/BMS-2.png 916w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/BMS-2-300x194.png 300w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/02\/BMS-2-768x496.png 768w\" sizes=\"auto, (max-width: 916px) 100vw, 916px\" \/><\/a><\/figure><div class=\"wp-block-media-text__content\">\n<p><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/mindset-2\/\">MINDSET 2<strong>: A Study to Evaluate the&nbsp;Efficacy&nbsp;and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer&#8217;s Disease&nbsp;<\/strong><\/a><\/p>\n\n\n\n<p>A clinical trial to see if the medicines KarXT and KarX-EC can help improve memory and thinking for people with <strong>Alzheimer\u2019s disease.<\/strong><\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group has-standard-white-background-color has-background\" style=\"border-top-left-radius:50px;border-top-right-radius:50px;border-bottom-left-radius:50px;border-bottom-right-radius:50px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading\">Other Ongoing Studies <\/h2>\n\n\n\n<h4 class=\"wp-block-heading\"><em>Closed to recruitment<\/em><\/h4>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:35% auto\"><figure class=\"wp-block-media-text__media\"><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/deep-frequent-phenotyping-study-dfp\/\"><img loading=\"lazy\" decoding=\"async\" width=\"916\" height=\"592\" src=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/DPUK.png\" alt=\"DPUK\" class=\"wp-image-2371 size-full\" srcset=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/DPUK.png 916w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/DPUK-300x194.png 300w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/DPUK-768x496.png 768w\" sizes=\"auto, (max-width: 916px) 100vw, 916px\" \/><\/a><\/figure><div class=\"wp-block-media-text__content\">\n<p><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/deep-frequent-phenotyping-study-dfp\/\" data-type=\"page\" data-id=\"1315\">DFP<strong>: Combinatorial Biomarkers for Dementia Experimental Medicine<\/strong><\/a><\/p>\n\n\n\n<p>A research study trying to better understand a person&#8217;s risk for developing <strong>Alzheimer&#8217;s Disease<\/strong>, using digital cognitive assessments and blood tests.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:35% auto\"><figure class=\"wp-block-media-text__media\"><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/evoke-evoke\/\"><img loading=\"lazy\" decoding=\"async\" width=\"917\" height=\"591\" src=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/EVOKE.png\" alt=\"EVOKE\" class=\"wp-image-2369 size-full\" srcset=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/EVOKE.png 917w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/EVOKE-300x193.png 300w, https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-content\/uploads\/sites\/111\/2026\/03\/EVOKE-768x495.png 768w\" sizes=\"auto, (max-width: 917px) 100vw, 917px\" \/><\/a><\/figure><div class=\"wp-block-media-text__content\">\n<p><a href=\"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/evoke-evoke\/\">EVOKE\/ EVOKE+<strong>: Investigating Semaglutide in People with Early Alzheimer\u2019s Disease \u200b<\/strong><\/a><\/p>\n\n\n\n<p>A clinical trial to see if the medicine Semaglutide&nbsp;can help slow down memory and thinking problems for people with <strong>Alzheimer\u2019s disease.<\/strong><\/p>\n<\/div><\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div id=\"contact\" class=\"wp-block-getwid-section minifooter2 gowide alignfull getwid-section-content-full-width\"><div class=\"wp-block-getwid-section__wrapper getwid-padding-left-large getwid-padding-right-large getwid-padding-tablet-top-medium getwid-padding-tablet-bottom-large getwid-padding-tablet-left-medium getwid-padding-tablet-right-medium getwid-padding-mobile-top-medium getwid-padding-mobile-bottom-normal getwid-padding-mobile-left-medium getwid-padding-mobile-right-medium getwid-margin-left-none getwid-margin-right-none\" style=\"min-height:400px;padding-top:10px;padding-bottom:50px\"><div class=\"wp-block-getwid-section__inner-wrapper\"><div class=\"wp-block-getwid-section__background-holder\"><div class=\"wp-block-getwid-section__background\"><\/div><div class=\"wp-block-getwid-section__foreground\"><\/div><\/div><div class=\"wp-block-getwid-section__content\"><div class=\"wp-block-getwid-section__inner-content\">\n<div class=\"wp-block-group\" style=\"padding-bottom:0px\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"footytext has-accent-colour-color has-text-color\"><strong>CONTACT INFORMATION<\/strong><\/p>\n\n\n\n<p>Neuroprogressive &amp;&nbsp;Dementia Research Network Office<\/p>\n\n\n\n<p><br>Old Pharmacy Building<br>Western General Hospital<br>Edinburgh <br>EH4 2XU<\/p>\n\n\n\n<p>Email: <a href=\"mailto:loth.sdcrn@nhs.scot\">loth.sdcrn@nhs.scot<\/a><\/p>\n\n\n\n<p>Telephone: <strong>0131 537 3804<\/strong><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"footytext has-accent-colour-color has-text-color\"><strong>ABOUT US<\/strong><\/p>\n\n\n\n<p>The NRS Neuroprogressive Disease and Dementia Network team in NHS Lothian conduct commercial and investigator led studies for: Alzheimer&#8217;s disease, Parkinson&#8217;s disease, Huntington&#8217;s disease, Motor Neurone Disease, dementia with Lewy bodies, Progressive Supranuclear Palsy and Multiple System Atrophy.<\/p>\n\n\n\n<p><sub><strong>\u00a9 NHS LOTHIAN | YOUR SERVICE.<\/strong><\/sub><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div><\/div><\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>We are currently running a range of dementia research studies across Edinburgh and the Lothians. Some of our studies are also taking place in other parts of Scotland. If you are interested in participating in research, you can&nbsp;register online&nbsp;or email us: loth.sdcrn@nhs.scot By taking part, you can help advance understanding, improve treatments, and shape the<\/p>\n","protected":false},"author":382,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[],"class_list":["post-2118","page","type-page","status-publish","hentry"],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"marianmontanha","author_link":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/author\/marianmontanha\/"},"rttpg_comment":0,"rttpg_category":false,"rttpg_excerpt":"We are currently running a range of dementia research studies across Edinburgh and the Lothians. Some of our studies are also taking place in other parts of Scotland. If you are interested in participating in research, you can&nbsp;register online&nbsp;or email us: loth.sdcrn@nhs.scot By taking part, you can help advance understanding, improve treatments, and shape the","_links":{"self":[{"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/pages\/2118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/users\/382"}],"replies":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/comments?post=2118"}],"version-history":[{"count":9,"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/pages\/2118\/revisions"}],"predecessor-version":[{"id":2455,"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/pages\/2118\/revisions\/2455"}],"wp:attachment":[{"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/media?parent=2118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/services.nhslothian.scot\/neuroprogressiveanddementianetwork\/wp-json\/wp\/v2\/categories?post=2118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}