Collaborate is now open to recruitment!
THE STUDY
COLLABORATE is an efficient, UK-wide, real-world-data-enabled, adaptive, 2-randomisation, controlled trial to determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing necrotising enterocolitis, mortality, and cognitive impairment in extremely preterm babies.
STUDY GOALS
- Randomisation 1 will determine if pasteurised human donor milk or preterm formula affect NEC and other outcomes if a supplement for own mother’s milk is required.
- Randomisation 2 will determine if routine macronutrient fortification of human milk is beneficial.
COLLABORATE is supported by NEC UK, Bliss, Adult Preemie Advocacy Network, The George Institute for Global Health, British Association for Neonatal Neurodevelopmental Follow-Up, British Association of Paediatric Surgeons and Neonatal Nurses Association.
