{"id":951,"date":"2025-02-14T12:40:00","date_gmt":"2025-02-14T12:40:00","guid":{"rendered":"https:\/\/services.nhslothian.scot\/bronchiectasis\/?page_id=951"},"modified":"2025-02-14T12:55:51","modified_gmt":"2025-02-14T12:55:51","slug":"assessing-chest-infection-treatment-response","status":"publish","type":"page","link":"https:\/\/services.nhslothian.scot\/bronchiectasis\/research\/completed-projects\/assessing-chest-infection-treatment-response\/","title":{"rendered":"Assessing Chest Infection Treatment Response"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignleft size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"198\" src=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/02\/port-300x198-1.jpg\" alt=\"port 300x198\" class=\"wp-image-952\"\/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">In treating chest infections,&nbsp;the study determined what indicators are useful for assessing treatment response.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><div class=\"wpcp-wp-lightbox-host wpcp-advanced-image-lightbox-icon-hover\"><a class=\"wpcp-wp-lightbox-image-link\" href=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/02\/IV.doc-164x300-1.jpg\" data-wpcp-wp-lb-image=\"1\"><img loading=\"lazy\" decoding=\"async\" width=\"164\" height=\"300\" src=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/02\/IV.doc-164x300-1.jpg\" alt=\"IV.doc 164x300\" class=\"wp-image-953\"\/><\/a><a href=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/02\/IV.doc-164x300-1.jpg\" data-fancybox=\"wpcp-wp-img-953\" class=\"wpcp-lightbox-trigger wpcp-advanced-image-lightbox-icon wpcp-position-top-right wpcp-advanced-image-lightbox-icon-hover wpcp-global-lightbox-icon wpcp-lightbox-icon--global wpcp-lb-icon-style-default\" data-wpcp-lb-icon-source=\"global\" aria-label=\"Open image in lightbox\" data-thumb-src=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/02\/IV.doc-164x300-1.jpg\" data-wpcp-lb-single=\"1\"><span class=\"wpcp-icon-container\"><svg viewBox=\"0 0 20 20\"><path d=\"M17.6585 16.025L14.2437 12.6198C15.1716 11.3338 15.6121 9.7613 15.4871 8.1819C15.362 6.60251 14.6795 5.11847 13.5607 3.99351C12.936 3.36206 12.1916 2.86066 11.3709 2.51845C10.5502 2.17623 9.66952 2 8.77995 2C7.89039 2 7.00969 2.17623 6.18899 2.51845C5.36829 2.86066 4.62395 3.36206 3.99919 3.99351C3.36594 4.61649 2.86312 5.35871 2.51992 6.17708C2.17673 6.99545 2 7.87365 2 8.76068C2 9.64772 2.17673 10.5259 2.51992 11.3443C2.86312 12.1627 3.36594 12.9049 3.99919 13.5279C5.11957 14.6901 6.62279 15.4103 8.23285 15.5562C9.84291 15.7022 11.4517 15.2641 12.7639 14.3224L16.1788 17.7275C16.3849 17.9034 16.6473 18 16.9186 18C17.1899 18 17.4523 17.9034 17.6585 17.7275C18.1138 17.16 18.1138 16.5925 17.6585 16.025ZM5.59278 12.0523C5.16258 11.6298 4.82094 11.1263 4.58774 10.5709C4.35455 10.0156 4.23446 9.41951 4.23446 8.81744C4.23446 8.21536 4.35455 7.6193 4.58774 7.06394C4.82094 6.50859 5.16258 6.00503 5.59278 5.58257C6.01644 5.15359 6.52144 4.81292 7.07838 4.58039C7.63532 4.34786 8.23308 4.22811 8.83687 4.22811C9.44066 4.22811 10.0384 4.34786 10.5954 4.58039C11.1523 4.81292 11.6573 5.15359 12.081 5.58257C12.5112 6.00503 12.8528 6.50859 13.086 7.06394C13.3192 7.6193 13.4393 8.21536 13.4393 8.81744C13.4393 9.41951 13.3192 10.0156 13.086 10.5709C12.8528 11.1263 12.5112 11.6298 12.081 12.0523C11.6573 12.4813 11.1523 12.822 10.5954 13.0545C10.0384 13.287 9.44066 13.4068 8.83687 13.4068C8.23308 13.4068 7.63532 13.287 7.07838 13.0545C6.52144 12.822 6.01644 12.4813 5.59278 12.0523Z\" \/><\/svg><\/span><\/a><\/div><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">The study investigated treatment response in those that were treated with intravenous antibiotic&nbsp;&nbsp;therapy&nbsp;(antibiotics delivered into the veins)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this study 8 indicators were considered; sputum colour; 24 hour sputum volume; spirometry (that is breathing tests); blood tests (white cell count and proteins that measure inflammation called C Reactive Protein and Erythrocyte Sedimentation Rate); sputum analysis for bacteria; quality of life questionnaires; and exercise tolerance.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Key Conclusions:<\/strong>The best indicators were: sputum colour; sputum volume; sputum analysis for bugs; blood test (proteins that measure inflammation); and quality of life questionnaires.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A good treatment response is when:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>you cough up less or no sputum, and if you produce any sputum it is a lighter colour or colourless.<\/li>\n\n\n\n<li>we cannot grow bacteria when we send the sputum sample to the microbiology laboratory.<\/li>\n\n\n\n<li>your blood tests show a reduction in your white cell count, C reactive protein and Erythrocyte Sedimentation Rate.<\/li>\n\n\n\n<li>your quality of life questionnaires show that you feel better.<\/li>\n\n\n\n<li>your exercise capacity improves.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Patient Implications:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is important you get assessments at the beginning and end of intravenous antibiotic therapy to assess the effectiveness of the therapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Reference:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">European Respiratory Journal. 2009 Feb;33(2):321-8<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In treating chest infections,&nbsp;the study determined what indicators are useful for assessing treatment response. The study investigated treatment response in those that were treated with intravenous antibiotic&nbsp;&nbsp;therapy&nbsp;(antibiotics delivered into the veins) In this study 8 indicators were considered; sputum colour; 24 hour sputum volume; spirometry (that is breathing tests); blood tests (white cell count and<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":933,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_gspb_post_css":"","_searchwp_excluded":"","footnotes":""},"categories":[],"class_list":["post-951","page","type-page","status-publish","hentry"],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"NHS Lothian","author_link":"https:\/\/services.nhslothian.scot\/bronchiectasis\/blog\/author\/nhs-lothian\/"},"rttpg_comment":0,"rttpg_category":false,"rttpg_excerpt":"In treating chest infections,&nbsp;the study determined what indicators are useful for assessing treatment response. The study investigated treatment response in those that were treated with intravenous antibiotic&nbsp;&nbsp;therapy&nbsp;(antibiotics delivered into the veins) In this study 8 indicators were considered; sputum colour; 24 hour sputum volume; spirometry (that is breathing tests); blood tests (white cell count and","_links":{"self":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/comments?post=951"}],"version-history":[{"count":1,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/951\/revisions"}],"predecessor-version":[{"id":954,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/951\/revisions\/954"}],"up":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/933"}],"wp:attachment":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/media?parent=951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/categories?post=951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}