{"id":1268,"date":"2025-11-06T12:44:00","date_gmt":"2025-11-06T12:44:00","guid":{"rendered":"https:\/\/services.nhslothian.scot\/bronchiectasis\/?page_id=1268"},"modified":"2025-11-06T12:44:49","modified_gmt":"2025-11-06T12:44:49","slug":"boat-trial","status":"publish","type":"page","link":"https:\/\/services.nhslothian.scot\/bronchiectasis\/research\/boat-trial\/","title":{"rendered":"BOAT Trial"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><div class=\"wpcp-wp-lightbox-host wpcp-advanced-image-lightbox-icon-hover\"><a class=\"wpcp-wp-lightbox-image-link\" href=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3.png\" data-wpcp-wp-lb-image=\"1\"><img loading=\"lazy\" decoding=\"async\" width=\"903\" height=\"677\" src=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3.png\" alt=\"image\" class=\"wp-image-1106\" srcset=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3.png 903w, https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3-300x225.png 300w, https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3-768x576.png 768w\" sizes=\"auto, (max-width: 903px) 100vw, 903px\" \/><\/a><a href=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3.png\" data-fancybox=\"wpcp-wp-img-1106\" class=\"wpcp-lightbox-trigger wpcp-advanced-image-lightbox-icon wpcp-position-top-right wpcp-advanced-image-lightbox-icon-hover wpcp-global-lightbox-icon wpcp-lightbox-icon--global wpcp-lb-icon-style-default\" data-wpcp-lb-icon-source=\"global\" aria-label=\"Open image in lightbox\" data-thumb-src=\"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-content\/uploads\/sites\/153\/2025\/07\/image-3-300x225.png\" data-wpcp-lb-single=\"1\"><span class=\"wpcp-icon-container\"><svg viewBox=\"0 0 20 20\"><path d=\"M17.6585 16.025L14.2437 12.6198C15.1716 11.3338 15.6121 9.7613 15.4871 8.1819C15.362 6.60251 14.6795 5.11847 13.5607 3.99351C12.936 3.36206 12.1916 2.86066 11.3709 2.51845C10.5502 2.17623 9.66952 2 8.77995 2C7.89039 2 7.00969 2.17623 6.18899 2.51845C5.36829 2.86066 4.62395 3.36206 3.99919 3.99351C3.36594 4.61649 2.86312 5.35871 2.51992 6.17708C2.17673 6.99545 2 7.87365 2 8.76068C2 9.64772 2.17673 10.5259 2.51992 11.3443C2.86312 12.1627 3.36594 12.9049 3.99919 13.5279C5.11957 14.6901 6.62279 15.4103 8.23285 15.5562C9.84291 15.7022 11.4517 15.2641 12.7639 14.3224L16.1788 17.7275C16.3849 17.9034 16.6473 18 16.9186 18C17.1899 18 17.4523 17.9034 17.6585 17.7275C18.1138 17.16 18.1138 16.5925 17.6585 16.025ZM5.59278 12.0523C5.16258 11.6298 4.82094 11.1263 4.58774 10.5709C4.35455 10.0156 4.23446 9.41951 4.23446 8.81744C4.23446 8.21536 4.35455 7.6193 4.58774 7.06394C4.82094 6.50859 5.16258 6.00503 5.59278 5.58257C6.01644 5.15359 6.52144 4.81292 7.07838 4.58039C7.63532 4.34786 8.23308 4.22811 8.83687 4.22811C9.44066 4.22811 10.0384 4.34786 10.5954 4.58039C11.1523 4.81292 11.6573 5.15359 12.081 5.58257C12.5112 6.00503 12.8528 6.50859 13.086 7.06394C13.3192 7.6193 13.4393 8.21536 13.4393 8.81744C13.4393 9.41951 13.3192 10.0156 13.086 10.5709C12.8528 11.1263 12.5112 11.6298 12.081 12.0523C11.6573 12.4813 11.1523 12.822 10.5954 13.0545C10.0384 13.287 9.44066 13.4068 8.83687 13.4068C8.23308 13.4068 7.63532 13.287 7.07838 13.0545C6.52144 12.822 6.01644 12.4813 5.59278 12.0523Z\" \/><\/svg><\/span><\/a><\/div><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">&#8220;What are the differences&nbsp;between continuing on long term azithromycin compared to stopping it in patients living with bronchiectasis&#8221;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The study is run from Newcastle University by Prof DeSoyza but there are sites all around the UK helping, including NHS Lothian.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Who can participate?<\/strong><br>Patients aged 16 years old and over with clinically stable bronchiectasis and prescribed prophylactic azithromycin or an equivalent long-term macrolide for at least 90 days in the past 12 months due to reduce the risk of bronchiectasis exacerbations<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><u>What does the study involve?<\/u><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this study, patients will continue taking azithromycin or switch to a placebo for 12 months. The dosage will match what they were already taking, which could be 250mg once a day three times a week, 500mg once a day three times a week, or 250mg once a day every day. The medication will be taken orally.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Contact the Research team<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We recruit patients from within the Bronchiectasis Service across NHS Lothian.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For more information on any of these studies or to find out how you can help contact the team on:  <\/p>\n\n\n\n<p class=\"wp-block-paragraph\"> 0131 242 1852 or loth.bronchiectasisresearchgroup@nhs.scot<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Commercial Bronchiectasis studies:<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We participate as a site in many UK and worldwide commercial bronchiectasis studies.  We work with many coomercial drug and device companies.  <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Often these studies recruit only 2-3 patients at each study site and inclusion criteria is very niche.  Our experienced research and clinical team will be best placed to identify suitable patients and inform them of the opportunity to participate in these studies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Current commercial studies include new tablet, inhaled, nebuilsed and intravenous drug infusion treatments for bronchiectasis.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&ldquo;What are the differences&nbsp;between continuing on long term azithromycin compared to stopping it in patients living with bronchiectasis&rdquo; The study is run from Newcastle University by Prof DeSoyza but there are sites all around the UK helping, including NHS Lothian. Who can participate?Patients aged 16 years old and over with clinically stable bronchiectasis and prescribed<\/p>\n","protected":false},"author":414,"featured_media":0,"parent":930,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_gspb_post_css":"","_searchwp_excluded":"","footnotes":""},"categories":[],"class_list":["post-1268","page","type-page","status-publish","hentry"],"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"andreaclarke","author_link":"https:\/\/services.nhslothian.scot\/bronchiectasis\/blog\/author\/andreaclarke\/"},"rttpg_comment":0,"rttpg_category":false,"rttpg_excerpt":"&ldquo;What are the differences&nbsp;between continuing on long term azithromycin compared to stopping it in patients living with bronchiectasis&rdquo; The study is run from Newcastle University by Prof DeSoyza but there are sites all around the UK helping, including NHS Lothian. Who can participate?Patients aged 16 years old and over with clinically stable bronchiectasis and prescribed","_links":{"self":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/1268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/users\/414"}],"replies":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/comments?post=1268"}],"version-history":[{"count":1,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/1268\/revisions"}],"predecessor-version":[{"id":1269,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/1268\/revisions\/1269"}],"up":[{"embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/pages\/930"}],"wp:attachment":[{"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/media?parent=1268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/services.nhslothian.scot\/bronchiectasis\/wp-json\/wp\/v2\/categories?post=1268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}